Security teams intercepted more than 400 kilograms of bhang valued at Sh10 million along the Mwingi-Garissa highway.
Two suspects who were ferrying the drugs in a lorry carrying cows to Nairobi were arrested in the Thursday afternoon operation.
Police said the cargo was hidden in a false compartment in the lorry.
"The narcotics were destined for Kiamaiko area in Huruma where a supplier was waiting to pick them up," police said.
Police further said the Kiamaiko area is Nairobi’s main hub for cannabis storage and packaging.
The head of the Anti Narcotics Unit Samuel Laboso said they have stepped up the crackdown against drug traffickers who continue to procure drugs at the detriment of the country.
Moyale town, the largest of the trading centres stands out as the capital of contraband that includes smuggling of Kenya’s popular variety of bhang.
Apart from Moyale, other border points used by the crooks to smuggle in bhang include Sololo, Uran, Forolle and Dukana.
Police say dealers use peddlers to bring the bhang into Kenya in small batches using unofficial or unpatrolled routes to smuggle in the contraband, especially at night.
Light vehicles, boda-boda, donkey carts and couriers are also used to sneak in the cargo undetected along the border.
It is from these centres that the bhang is transported to Nairobi using two different routes, the direct Moyale-Nairobi highway via Marsabit town and Isiolo and the unofficial route, a cutline that runs from Funannyata in Sololo to Yamicha plains of Merti sub-county in Isiolo.
More attention is being put on the route to stop the trend, police said.
Laboso said separate police units have been cracking down on gangs behind the cases of drug trafficking in the country.
