Liverpool will face Paris St-Germain in the Champions League last 16, while Arsenal take on PSV Eindhoven and Aston Villa will play Club Brugge.
Holders Real Madrid face local rivals Atletico Madrid and Bayern Munich play Bayer Leverkusen in an all-Germany affair.
The winners of that tie will face Aston Villa or Club Brugge in the quarterfinals, while Arsenal will meet record 15-time winners Real Madrid or Atletico Madrid in the last eight—should they get past PSV.
The two-legged last 16 ties will be played on 4-5 March and 11-12 March.
Last-16 draw in full
Paris St-Germain v Liverpool
Real Madrid v Atletico Madrid
Feyenoord v Inter Milan
Borussia Dortmund v Lille
Club Brugge v Aston Villa
PSV Eindhoven v Arsenal
Bayern Munich v Bayer Leverkusen
Benfica v Barcelona