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Top 15 causes of death worldwide in 2021

Tuberculosis (TB) remains a leading cause of death, especially among people with HIV.

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by Hillary Bett

Infographics31 October 2024 - 15:01
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In Summary


    Top 15 causes of death worldwide in 2021


    In 2021, ischemic heart disease was the leading global cause of death, claiming millions of lives.

    This was closely followed by COVID-19, highlighting the pandemic’s profound impact on global mortality rates.

    Stroke, chronic obstructive pulmonary disease (COPD), and lower respiratory infections also ranked high among fatal conditions, underscoring the burden of non-communicable and respiratory illnesses.

    The chart illustrates the significant death toll associated with diseases like Alzheimer’s, diabetes, and kidney diseases. Tuberculosis (TB) remains a leading cause of death, especially among people with HIV, represented in blue on the graph.

    Road injuries, liver diseases, and cancers such as those affecting the trachea, bronchus, lung, colon, and rectum are also highlighted, reflecting the global diversity of health challenges.

    This data, sourced from the World Health Organization's 2024 Global Tuberculosis Report, provides a sobering perspective on the range of deadly conditions affecting populations worldwide.

    Deaths from TB among people with HIV are officially classified as deaths caused by HIV/AIDS in the International Classification of Diseases.

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