At least 11 people were killed and dozens more were injured in a Russian strike on Dobropillya, according to Ukrainian authorities.
The town lies northwest of Russian-held Donetsk city.
Eight residential buildings and an administrative building were damaged in the attack late on Friday, the regional emergency service reported.
"Russia kills civilians," says Donetsk regional head Vadym Filashkin in a Telegram post this morning.
He says the number of people killed in the Donetsk region rose to 20 on Friday, with another 43 injured.
The regional head also says the latest figures don't include those injured in Mariupol and Volnovakha, which are currently under Russian military control.
Major Volodymyr Omelyan from the Brigade of Armed Forces of Ukraine has described the attack in Dobropillya as "typical".
"In this particular case, there was a missile strike. There are daily invasion bomb strikes in the Donetsk region," Omelyan tells BBC Radio 5 Live Breakfast.
"Civilians are getting hurt and getting killed every day."
Maj Volodymyr Omelyan, says Ukraine will keep fighting "because there is no other option for us".
"Russians are extremely inspired by recent statements of Trump that he's leaving Europe, he's going to remove sanctions against Russia, cutting Ukrainian intelligence and also supplies," Omelyan says.
Reacting to news from the US overnight that Washington has revoked access to satellite imagery, Omelyan says it is now "like fighting blind."
"We don't see what Russia is preparing to do on its territory anymore," he adds. "It's very difficult to see the main direction of their future attacks and supplies.
"You hear the noise and feel the enemy but you cannot see it."
