Police officers were on standby in Kisumu as residents took to the streets to answer Azimio leader Raila Odinga's call for protest.
Raila had rallied his supporters across the country to mark the historic Saba Saba Day by protesting against the government over the high cost of living.
Various roads had been blocked as tires lit along the roads with minimal movement witnessed.
Shops and businesses remained closed within Lakeside City as residents opted to stay indoors to avoid confrontation with the protestors.
A procession was seen coming from Kondele towards town with residents carrying placards while chanting anti-government slogans as they sang and danced along the streets.
They said Kenyans are bedevilled by the high cost of living, high food prices, high taxation and corruption.
"Enough is enough, we cannot continue to live in such a manner where Kenyans are not able to put food on the table," they said.
Police officers were on standby within Kisumu Boys roundabout and Patels roundabout, Agah Khan roundabout and even the Kibuye area.
On Thursday, members of various civil society organizations and human rights activists under the People Power Movement asked the police to obey the law and to conduct themselves professionally as stipulated in the Constitution during the protest.
"We urge them to rewrite the all-too-familiar narrative where they are used to disrupt protests instead of supporting protests and the grievances behind them, though they too are victims of this brutal system that only owes loyalty to the owners of capital," they said.
They also asked Kisumu residents to ensure that the activities are peaceful.
"Criminals who try to take advantage of the situation, if any at all, should be arrested and handed over to the police. We must not allow any individual or group of people to delegitimize our protests," they said.
